Chronic Cocaine Exposure During Pregnancy Increases Postpartum Neuroendocrine Stress Responses
نویسندگان
چکیده
منابع مشابه
Chronic cocaine exposure during pregnancy increases postpartum neuroendocrine stress responses.
The cycle of chronic cocaine (CC) use and withdrawal results in increased anxiety, depression and disrupted stress-responsiveness. Oxytocin and corticosterone (CORT) interact to mediate hormonal stress responses and can be altered by cocaine use. These neuroendocrine signals play important regulatory roles in a variety of social behaviours, specifically during the postpartum period, and are sen...
متن کاملEffects of Prenatal Cocaine Exposure on Human Pregnancy and Postpartum
Substance abuse in pregnancy has increased over the past three decades in the United States [1]. A National survey on drug Use and Health from 2002-2003 has estimated that 4.3% of pregnant women aged 15-44 years reported illicit drug use within the month to being questioned [1,2]. Approximately 250,000 women in the United State, of whom 90% are of childbearing age with criteria for intravenous ...
متن کاملFluoxetine exposure during adolescence increases preference for cocaine in adulthood
Currently, there is a high prevalence of antidepressant prescription rates within juvenile populations, yet little is known about the potential long-lasting consequences of such treatments, particularly on subsequent responses to drugs of abuse. To address this issue at the preclinical level, we examined whether adolescent exposure to fluoxetine (FLX), a selective serotonin reuptake inhibitor, ...
متن کاملAcute neonatal effects of cocaine exposure during pregnancy.
OBJECTIVE To identify associations between cocaine exposure during pregnancy and medical conditions in newborn infants from birth through hospital discharge. DESIGN Multisite, prospective, randomized study. SETTING Brown University, University of Miami, University of Tennessee (Memphis), and Wayne State University. Subjects A total of 717 cocaine-exposed infants and 7442 nonexposed infants....
متن کاملStress during first pregnancy increases seizure threshold in adult male offspring
Objective(s): Stress induces many homeostatic aberrations which are followed by lifelong allostatic responses. Epilepsy is developed or influenced by different environmental factors, i.e. prenatal stress which makes many contradictory developmental changes in seizure threshold and intensity. We investigated the potential seizure response of the rat offspring to prenatal stress; the stres...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neuroendocrinology
سال: 2012
ISSN: 0953-8194
DOI: 10.1111/j.1365-2826.2012.02291.x